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Intercourse variations in COVID-19 outcomes

PICTURE: Dedicated to diseases and conditions that are more at risk for women or more common in women, as well as diseases that are different in women. view More

Photo credit: Mary Ann Liebert, Inc., editor

In a study of more than 10,600 adult patients hospitalized with COVID-19, women had a significantly lower likelihood of hospital death than men. They also had fewer ICU admissions and less need for mechanical ventilation. According to an article in the peer-reviewed Journal of Women’s Health, women were also significantly less likely to have serious adverse events, including acute heart injury, acute kidney damage, and venous thromboembolism. Click here to read the article now.

“This comprehensive analysis is the largest study to date that directly assesses the effects of sex on COVID-19 outcomes,” said Rachel-Maria Brown, MD, Zucker School of Medicine at Hofstra / Northwell, and co-authors. “Our study clearly shows that females are associated with lower chances of hospital outcomes, serious side effects, and all-cause mortality compared to males after controlling for confounding variables.” The authors suggest some of the protective factors that may contribute to these results.

In the accompanying editorial titled “Lessons Learned from COVID-19 Sex Disparities,” Annabelle Santos Volgman, MD, Rush University Medical Center, and co-authors suggest various mechanisms that give women a protective advantage against COVID-19 infection can offer. One benefit could be the extra X chromosome, which carries several genes that are responsible for innate and adaptive immunity.

Volgman and co-authors emphasize, “Although women with COVID-19 have a lower risk of death, we must use caution not to send a message to provide substandard care for women with COVID-19 or to reduce measures to prevent their infection. Our evolving knowledge should not reduce attention to women admitted for COVID-19. ”


The research reported in this publication was supported by the National Institutes of Health under price number R24AG064191, R01LM012836, R01 NR018443. The authors are solely responsible for their content and do not necessarily represent the official views of the National Institutes of Health.

About the magazine

The monthly Journal of Women’s Health is a core multidisciplinary journal devoted to diseases and conditions that are at higher risk for women, or more common in women, and diseases that are different in women. Under the direction of Editor-in-Chief Susan G. Kornstein, MD, Executive Director of the Virginia Commonwealth University Institute for Women’s Health, Richmond, VA, the journal covers the latest advances and clinical applications of new diagnostic procedures and therapeutic protocols for the prevention and management of women’s health issues. Full tables of contents and a sample edition can be found on the Journal of Women’s Health website. Journal of Women’s Health is the official journal of the Society for Women’s Health Research.

About the publisher

Mary Ann Liebert, Inc. is known for establishing authoritative, peer-reviewed journals in many exciting areas of science and biomedical research. A full list of the

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